ZELGOR - 500MG (Applepharmaceutical)

ZELGOR - 500MG  (Applepharmaceutical)

Abiraterone is sold under brand name Zelgor 500mg ,( zelgor 500mg price in india ) belongs to type of anti-cancer medication that will act by a decline the androgen production in the body.
Androgen is a male hormone that can maintain the tumor cell in prostate glands.
This drug is given by co-administration with prednisolone, a steroid which reduces the liability of side effects produced by Abiraterone.

DOSAGE

The prescribed dose of  zelgor 500mg price in indiais initial as 4 tablets given orally once daily.
The drug Zelgor administrated combination with 5mg prednisolone twice daily in empty stomach.
• Zelgor 500mg Tablets given on an empty stomach.
• Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zelgor Tablets is taken. • Swallowed whole with water. • Chew the tablets or Do not crush

Zelgor 500mg

MECHANISM OF ACTION :

Androgens are balance the production of malignant in prostate.

Zelgor 500mg belongs to anti androgen drugs, that causes to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involving in androgen conglomerate.

Reduce the serum testosterone level.

Declined the tumor cell occurred.

PHARMACOKINETICS

Absorption:

Time to maximum plasma concentration of Zelgor 500mg tablet takes 12 hours.

Distribution:

Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein.

Metabolism:

The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate.

Excretion:

The drug mainly excreted in 88% feces and 5% in urine

Half-life of tablet Zelgor 500mg is 12 ± 5 hours.

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